BEYONDH0ANDq0: COSMOLOGY IS NO LONGER JUST TWO NUMBERS

BEYOND H[subscript 0] AND q[subscript 0]: COSMOLOGY IS NO LONGER JUST TWO NUMBERS

For decades, H0 and q0 were the quest of cosmology, as they promised to characterize our “world model” without reference to a specific cosmological framework. Using Monte Carlo simulations, we show that q0 cannot be directly measured using distance indicators with both accuracy (without offset away from its true value) and precision (small error bar). While H0 can be measured with accuracy and ...

Runx1: no longer just for leukemia.

Some 20 years after original work positioned Runx1 as crucial for haematopoiesis and leukaemia formation (Miyoshi et al, 1991; Okuda et al, 1996), a study in this issue of the EMBO Journal (Scheitz et al, 2012) reveals that the RUNX1/Stat3 axis also promotes carcinogenesis in epithelial tissues. RUNX1, the DNA-binding subunit of heterodimeric transcription factor CBF, was first identified as a ...

CMAJ no longer just a Canadian journal, eCMAJ survey indicates.

Autophagosomes and lipid droplets: no longer just chewing the fat.

Autophagosomes are organelles capable of sequestering and degrading diverse cytoplasmic cargo for nutritional and quality control purposes. Targeted are also lipid droplets (LDs), the cytoplasmic stores of neutral lipids. In this issue of The EMBO Journal, Shpilka et al (2015) show that the relationship between LDs and autophagosomes is far more intricate and that LDs regulate autophagosome bio...

No longer ignored, AIDS funds just keep growing.

* SCIENCE Is published weekly on Friday, except the last wmek In December, and with an extra Issue In February by the American Association for the Advancement of Science, 1333 H Street, NW, Washington, DC 20005. Second-class postage (publication No. 484460) paid at Washington, DC, and at an additional entry. Now combined with The Scientific Monthly® Copyright C 1988 by the American Association ...